Prevalencia de psoriasis en pacientes con Síndrome de Down
DOI:
https://doi.org/10.14409/sigme.2023.1.e0005Keywords:
psoriasis, Down syndrome, prevalenceAbstract
Psoriasis (Ps) is one of the dermatoses that can affect patients with Down syndrome (DS). Its clinical presentation is varied, severe forms have been reported, in some cases associated with arthritis being atopic dermatitis, seborrheic dermatitis, xeroderma, and keratoderma are the most frequent cutaneus findings in this population. Our aim was to determine the Ps prevalence in DS, through out an observational, descriptive and cross-sectional work. Our results showed a prevalence of 8.33% in 60 patients with DS examined. We conclude that Ps probability is higher in patients with DS than without.
References
Chavarría, C., Casanova, M. J., Chaparro, M., Barreiro-de Acosta, M., Ezquiaga, E., Bujanda, L., Rivero, M., Argüelles-Arias, F., Martín-Arranz, M. D., Martínez-Montiel, M. P., Valls, M., Ferreiro-Iglesias, R., Llaó, J., Moraleja-Yudego, I., Casellas, F., Antolín-Melero, B., Cortés, X., Plaza, R., Pineda, J. R., Navarro-Llavat, M., … Gisbert, J. P. (2019). Prevalence and Factors Associated With Fatigue in Patients With Inflammatory Bowel Disease: A Multicentre Study. Journal of Crohn's & colitis, 13(8), 996–1002. https://doi.org/10.1093/ecco-jcc/jjz024
Barry, K., Zancanaro, P., Casseres, R., Abdat, R., Dumont, N., & Rosmarin, D. (2021). Concomitant atopic dermatitis and psoriasis - a retrospective review. The Journal of dermatological treatment, 32(7), 716–720. https://doi.org/10.1080/09546634.2019.1702147
Di Meglio, P., Villanova, F., & Nestle, F. O. (2014). Psoriasis. Cold Spring Harbor perspectives in medicine, 4(8), a015354. https://doi.org/10.1101/cshperspect.a015354
Ercis, M., Balci, S., & Atakan, N. (1996). Dermatological manifestations of 71 Down syndrome children admitted to a clinical genetics unit. Clinical genetics, 50(5), 317–320. https://doi.org/10.1111/j.1399-0004.1996.tb02381.x
Fredriksson, T., & Pettersson, U. (1978). Severe psoriasis--oral therapy with a new retinoid. Dermatologica, 157(4), 238–244. https://doi.org/10.1159/000250839
Guttman-Yassky, E., Krueger, J. G., & Lebwohl, M. G. (2018). Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment. Experimental Dermatology, 27(4), 409-417. https://doi.org/10.1111/exd.13336
Iribas, J.L., Peralta, I., Ferraro, L. Y. y Ubogui, J. (2018). Adolescente Con Síndrome De Down Y Psoriasis Severa. Veintidos Meses De Tratamiento Con Etanercept. Revista Argentina de Dermatología.,99, (3), 61-70.
Kimball, A.B., Krueger, G. y Woolley, J.M. (2004). The Dermatology Life Quality Index (DLQI) Provides Qualitatively Different Information From The PASI. The Journal of the American Academy of Dermatology, 606.
Leung, D.Y. (2015). Atopic dermatitis: age and race do matter! Journal of Allergy and Clinical Immunology. 136, 1265-1267.
Makowska, K., Nowaczyk, J., Blicharz, L., Wa´sckiel Burnat, A., Czuwara, J., Olszewska, M. y Rudnicka, L. (2023). Review Immunopathogenesis of Atopic Dermatitis: Focus on Interleukins as Disease Drivers and Therapeutic Targets for Novel Treatments. International Journal of Molecular Sciences is an international, 24,781.
Marmon, S., De Souza, A. y Strober, B.E. (2012). Psoriasis and Down syndrome: A report of three cases and a potential pathophysiologic link. Dermatology Online Journal, 18 (6),13.
Martini, J., Bidondo, M. P., Duarte, S., Liascovich, R., Barbero, P. y Groisman, B. (2019). Prevalencia del síndrome de Down al nacimiento en Argentina. Saludcolectiva (15). https://dx.doi.org/10.18294/sc.2019.1863
Nomura, K. (1999). Ichthyosis and Psoriasis in a Patient with Down Syndrome. J of Dermatology 26, 538-540.
Parisi, R., Iskandar, I. Y. K., Kontopantelis, E., Augustin, M., Griffiths, C. E. M., Ashcroft, D. M., & Global Psoriasis Atlas (2020). National, regional, and worldwide epidemiology of psoriasis: systematic analysis and modelling study. BMJ (Clinical research ed.), 369, m1590. https://doi.org/10.1136/bmj.m1590
Polenghi, M.M., Piattoni, F., Orsini, G.B, Barcella, M.F., Gueli, M.R., Leuzzi, S., Gualandri, V. (1990). Dermatologic Disorders In Down Syndrome. The American Journal of Medical Genetics,7, 324-325.
Raharja, A., Mahil, S.K. y Barker, J.N. (2021). Psoriasis: a brief overview. Clinical Medicine 21(3),170–173.
Rotchford, J.P., Wash, S. y Hyman, A.B. (1961). Extreme Hyperkeratotic Psoriasis in a Mongoloid. Arch Dermatol,83,127-130.
Schepis, C., Baroneb, C., Siragusa, M., Pettinatob, R., Romanob, C. (2002). An Updated Survey on Skin Conditions in Down Syndrome. Dermatology 205,234–238.
Schepis, C., Siragusa, M. y Happlee, R. (2017). Psoriasis and Alopecia Areata in a Down Syndrome Patient: a Renbök phenomenon. The European Journal of Dermatology27,300- 301.
Słuczanowska-Głąbowska, S., Ziegler-Krawczyk, A., Szumilas, K., & Pawlik, A. (2021). Role of Janus Kinase Inhibitors in Therapy of Psoriasis. Journal of clinical medicine, 10(19), 4307. https://doi.org/10.3390/jcm10194307
Sugiura, K., Kitoh, T., Watanabe, D., Muto, M., & Akiyama, M. (2015). Childhood-onset PsA in Down syndrome with psoriasis susceptibility variant CARD14 rs11652075. Rheumatology (Oxford, England), 54(1), 197–199. https://doi.org/10.1093/rheumatology/keu419
Sureshbabu, R., Kumari, R., Ranugha, S., Sathyamoorthy, R., Udayashankar, C., & Oudeacoumar, P. (2011). Phenotypic and dermatological manifestations in Down Syndrome. Dermatology online journal, 17(2), 3.
Takeshita, J., Grewal, S., Langan, S. M., Mehta, N. N., Ogdie, A., Van Voorhees, A. S., & Gelfand, J. M. (2017). Psoriasis and comorbid diseases: Epidemiology. Journal of the American Academy of Dermatology, 76(3), 377–390. https://doi.org/10.1016/j.jaad.2016.07.064
Tan, Y., Qi, Q., Lu, C., Niu, X., Bai, Y., Jiang, C., Wang, Y., Zhou, Y., Lu, A. y Xiao, C. (2017). Citokine Imbalance as a Common Mexhanism in Both Psoriasis and Rheumatoid Arthritis. Mediators Inflamm. Doi:10.1155/2017/2405291.
Thomas, L., Augey, F., Chamchikh, N. y Barrut, D. (1994). Et Moulin G. Signes Cutanés De La Trisomie 21. Ann Dermatol Ven,121,346-350.
Torre, D. (2005). Serum Levels of Gamma Interferon in Patients with Down´s Syndrome. Infection, 23,66-67.
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Copyright (c) 2023 Mario José Salva, María Laura Vassallo, Francisco Quiñoñes, Gustavo Adolfo Staiger, Nair Marivel Preisz, Emiliano Chaves, Mariela Muller, Ignacio Diego Sverloff, Ana Albrecht, Rocío Páez, María Lucrecia Salva, María Eugenia Williner, María Gabriela Díaz, María Virginia Guardati, José Luis Ismael Iribas, Marcelo Carlos Nacucchio
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