Dengue en pacientes con síndrome febril inespecífico en el Hospital Orlando Alassia, Santa Fe.

Abstract

Dengue is a disease caused by a virus of the same name from the Flaviviridae family, being currently the most important arbovirus on our planet causing around five millions of annual infections. In Argentina, it occurs in a stationary epidemic form, producing an unprecedented increase in the numbers of the affected population in recent years. The objective of this work was to analyze the prevalence of Dengue in pediatric patients, who attended medical consultation, due to non-specific acute febrile syndrome, at the Doctor Orlando Alassia Hospital in the city of Santa Fe, in the period between January 2014 and June 2023. A retrospective, observational analytical study was carried out, first presenting the clinical and laboratory characteristics of patients diagnosed with Dengue. Subsequently, the hospitalization and mortality variables were analyzed in relation to sex, age, social risk, comorbidities, hemoconcentration, thrombocytopenia and hypertransaminasemia. 56 pediatric cases were computed. The most common clinical manifestation was fever, followed by nausea and vomiting. Laboratory abnormalities were thrombocytopenia, leukopenia, neutropenia, hypertransaminasemia and lymphocytosis. 11 patients had Dengue with Warning Signs. 14 patients were computed, with an average of 8.4 days of hospitalization. No deaths were recorded. A significant relationship was found between the evolution and the presence of comorbidities (p= 0.004). It was concluded that the recognition of warning signs, hematological control and associated comorbidities is essential to detect those at risk of developing Severe Dengue and offer them early support treatment.